A university lecturer, Prof. Christian Happi, has claimed that Yoruba
people, by the make-up of their genes, are immune to Lassa virus that
causes Lassa fever. The researcher, who is Dean, College of Postgraduate
Studies, Department of Biological Sciences, Redeemer’s University, Ede,
Osun State, said research was ongoing on why this is so, adding that
few cases of Lassa fever recorded among Yoruba people are “imported.”
Speaking on the new breakthrough on the rampaging Lassa fever, Happi,
who is Director, World Funded African Centre of Excellence for Genomics
of Infectious Diseases, ACEGID, while speaking in Ede, said Lassa fever
virus originated from Nigeria about 1,060 years ago. He further
explained that the disease spread to other West African countries about
400 years ago, stressing that Yoruba have capacity to resist the virus
more than any other ethnic group in country. He added, “Using next
generation sequencing approach, we have identified a signal of natural
selection in human gene called LARGE in the Yoruba populations of the
South-West of Nigeria that may be associated with protection to Lassa
fever virus. We have hypothesised the potential mechanisms of protection
and believe that this could be the key to the future Lassa fever
vaccine.” Meanwhile, a 28-year-old lady has died of Lassa fever in Ogun
State. The Ogun State Commissioner for Health, Dr. Babatunde Ipaye, said
that the young lady was the first to have died of the disease in the
state. Ipaye, who said this during a press conference held at Oke Mosan
in Abeokuta on Thursday, said the victim had travelled to Ebonyi for a
burial programme and returned to Ogun on January 15, and later started
manifesting the symptoms of the viral disease.
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